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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2e431f5506e044b6897f3d37da23122c2cfdf39c3cbc43143e7e2b246a263387' 
  AND token = 'aVLMZRLtWwDD0i7p9ADsTMQYqUEbXA+p4LuSpI4weao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}