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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2848e856388a0b40619637545218b00beb3bff6d4fd2f43c1594d16dcecb39fc' 
  AND token = 'wpfScYwUxGwR9iB12k3rHYOkXOiPvPaiEGEFgLf+bac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}