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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7e06c0302ae25e46aba8c116aa302a788d80449d8c61c4c36530b3453164b99e' 
  AND token = 'TsRCo6vwP3u+cdJGO3ZjhIH8/kaUJa0fUaSgGPAvCkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}