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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1630a1d2a53c1dc6d1cad2d1daf751470600ccef5d4e92cb7c43f6f4809197bc' 
  AND token = 'lO4Bg1nBgKNTChBiNCIup+Va/+26NtJo7cOwRMQ3bY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}