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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '37cfab8f53d06cded073c4990aa4a708063b26eb996ea107c2220f3c392936b5' 
  AND token = 'TEnMoZuV+kZI/vqpktYIsiz26PuapaAzK4TTa+6wE4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}