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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c622ac9da7ca729573243c476a5763637a2d9b186b6352aa63e9457b864c6216' 
  AND token = 'mF2ky6t/eMYulJXrwPcTBGJUTiCiwofZpFYwvQbrOBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}