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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '67d3e63d14bb61f6c3c4cb04a05a67369dd9306c4a6e58f01b359b1854bdd419' 
  AND token = 'tyXxz25XQR3AwU5/px1CtFEPudK2QyHfEKTCAw72u4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}