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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'be6af6e31a9167f99d583f3399498b07bce309a55379e7348117bcd4f21a98ff' 
  AND token = 'nATfIgyDdfhkPM3s1uPL4zrJaJKDDH9xPh3h19yIMz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}