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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '446e078d6fcac5627a582bee36f0e9dbd1415edcce6e6d1c7fbfc64f165931c1' 
  AND token = 'SqaymV2n6JdcSklvLJXeMia9+e6FiLon/JwXMQ4vXBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}