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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '081e3a23175ea38d2e59b45a54d89b5225f7a0215e577798830668686d79ebfe' 
  AND token = 'dKI7SSZtPUe0/+m/68OQ3EjT7uvliuUdI+mAG3KQWyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}