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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c8a4edc9a064519419eca7204bb25a44da9910de114dfbfda89c35dbab27dd4c' 
  AND token = 'W4Zk6VL9DMzCX2g7WmxxSBBIltVxKD84kGheWTzScCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}