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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2d53b3170788d285da50d8ed32b1dc70e0686bbd9a8a93637e79504c2bbc4f22' 
  AND token = 'adxy4rAozjPJEk5NspwtDiyp0cR6//geIBGJHcL7GNI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}