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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ce2b3a9f8264b1e8a3292beb66e4a39bbf1114fcbda3a76113ad40d434914745' 
  AND token = 'vtgIznoGY6n3Cb9DE9S8lDccrvIrcBFjqNPt0Rm2xBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}