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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6162b43f096f5a75c739e8c2e1250c2439dc8677333a153100a09de9ba4cfbca' 
  AND token = 'DZ8LOdUyMmi665RaD5lh7JJlOpM6dKhZv0zfjl/p4ZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}