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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '383ba919c80e07ea26323e531122c9805ee2e40ba24cf5ba40bde06eeb8f339b' 
  AND token = 'vN9V1bqIjsQG2Kx0kiYgJFdNcIMWW/lUN34o9o1ktFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}