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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '12390510917900c1871902cbccc431a491e77087ac49459dc321f6b5cd8ec946' 
  AND token = 'IM8dId6J3GOphK8yQDMRmARH/JrSbECf5hI1fnTjoEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}