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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a636a8d0525f88cdf76491e7290c1a4768fc4a8d60118c31fbe16c09818b49ae' 
  AND token = 'sYsaje/Fx9+vS1rbjJIAe4R9l5oSxt+4MXb9DB7GYYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}