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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c07d1a403aa62b0189a6a61e9b64c60a69c8fd172bf3885f7fa04364016a01f6' 
  AND token = 'NZE76hGmzygKiuxBZx/ItT8XYbMeI18kS0IRhXT29SM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}