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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e1025644c118709d6a0ad4f7f7cb2d5602e87aa1d27e101c445530d3090a0c51' 
  AND token = 'Fu7vBtZkg9cew4+DPlv30LjKP2TB+dMwy4nP7DF9sd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}