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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b597e876f0b186e163fd32424c1d6f7250d9125eaa72ab4b6ec2d7f81a757248' 
  AND token = 'ofrrDQ5hJqqcBbaBMPaCyH55OvtvlfcXV3THq96mycw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}