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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7d8899f00ca303dc2a232a83dc2ebc8ef4c980d0d01fbcf33900f448557f4477' 
  AND token = 'PdAXOB4V4LNuMKKiONwXrwiiUP1+IuHIi54VQeujTeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}