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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f4ad3e60bd679a6b4c3df81bb6b380ae8b4e08508914c313003657b53fef94f8' 
  AND token = 'g4hFH6YCXPMKtJcCJdXfoCVOZj5oWKdm70DN0uSAh9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}