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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '11889925a33cb1c78060448ec95372b7a1babb9c8b16a9ef4bb302eb19862df0' 
  AND token = 'lVoRXJSEK+iQom1oMLHmcutxHj+pE+rpoziu0y6ZBI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}