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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'db1e23da5806390a8fa06ffa95879d09651e1af1c9e75f51b1491f96634a8a9d' 
  AND token = 'a4Wg1bp1b5ch6QcXnrGWgQV0gRptmU7PmC+hOdYJSwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}