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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '180ddd20eb1020d0df80b3b0c0e4143198fbfd549f9cf5dff54d7f73c36d08a1' 
  AND token = 'TRR/aVqMxP1BVGbszV4xMDOlfEx4vJOpYAuSA3hkAZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}