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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a6c797634bd9b90a65ef91ce53f1889d76ccf673408072dab9b99f0fd52456d5' 
  AND token = 'CTcPZNKa3rG7Zp+3D6E24Gg1uhQ7AyXMYrC+3T9xj74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}