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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c8846ea79fd23d6a64489fb5ca4e517d05d0bdac31412f64dc9cbe0f6e92ea4d' 
  AND token = '46KjEg6lw6Li3BAAE2TfoSrQumtrQ/Lj4YtJFh3K6jA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}