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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd0bcfbdd05d38786d34829d390fd3705027fc70d6ca9caff3c45ca1171684f86' 
  AND token = 'nGmMkTSVBuLdNAAKXkIU/AFPn7sdSc5jrNDUHYs0Y8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}