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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '578997163307ae79f0222f65cfbc4cadf3c85fde8a3605aee58fe6f396393591' 
  AND token = 'j94SAXT8711Yke/fQFUe/XOoylwKbu7vlsFknVuuLt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}