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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'aea25cd8e012c447d25c2edb19f2e6109d6c7cb89d73ca218da2d7af8a2d9720' 
  AND token = '+hCXSUpZc2PFIsJ//U3WQWv0mWsQNKGIdvzrUBuZ1lI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}