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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5770703b98de1d796bca8800a8b8513ada22f8f1355d227894575c05181ba6fb' 
  AND token = 'xBTt3NfFGTevs6ZJUmzMy1a840S4gk9SDl0aiPbMbag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}