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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4726a21a17456887dbe6f2c6516545c4f296ff4a0bac8ab6f0961249dd0b50a1' 
  AND token = 'jPz1XqZr+ZPif9sj7iLiuD44+4MxueP55OFGZllZFV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}