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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0773de45a05cf4e2aa46a73e66223deeb34f1c2245dbec81e26933483a77d7c7' 
  AND token = 'HdP0NtDjcvOJGiJwKUbTx189cG1G1WxmfcNR9JysmcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}