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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b136ec155447e47de0e7e4e85fe8fa9475e0625ce680cb57150c7a53768c6f2e' 
  AND token = 'DMjAW+7vcAgtG/XkVRfgtHnWCJILO0+Qs2OVWHFl4W4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}