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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '78f2210cc53671854d89acbeadfcc6f2a8cf00a79eb4340ed2cc4300a29484bd' 
  AND token = 'ETKw1hKqMLV5wXklBEJT3aOCy9c7Mrd3zC8iW31Duz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}