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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e133db8d15ba1de8465f3a12b53d0369db0eeb0d7bb0f17a9e478aa81474353d' 
  AND token = 'YxNG5C4/EkvMsSMxF4DCObSOXTeSk/p20kBbguERzsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}