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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6a22d44f4f1f8bf6b44af871a78fbc6cbb5be19c05e5eee8477df95e80bde25e' 
  AND token = 'JdhldYlwScZnJ4ZhO+bVEKHVdF/9O0tKHNtGC+y1OHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}