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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3016432186f24e394d48166ab06c27c51bad61b7f1a212e753373fb7b84d5405' 
  AND token = 'uA/WuZ0+6OM+hKWNRS/LL6+T1/QEL/PrYO1nobA0eQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}