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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e3b775b16b05e21920a384407ac9ac242e104b2cedbd7122ee405a997edd20d3' 
  AND token = 'RK+2jX6YS9Q80N7yMHrKGRZTSag+b1FhisxUIPhCOzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}