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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e96c4df9cda62a404e4c75ece91bd64700053dcdfaa437b4cd922a6496149444' 
  AND token = 'VudWLW4MSpZUhEYdsajgGWFEkeTvStqngIVAn7FMJaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}