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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '64ac49f17d9e68a2c4c90eec693819bf56c1810912f446367926e86e8dc642f1' 
  AND token = 'U1PH2T3zXGWgZUC43V+ivAH7DE0MI/DJnrPSPd0DK2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}