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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a374b303893f2b9d80f244a6ab1c97898dea79f16f0eae253e7facb83b79f240' 
  AND token = 's2ghl7a9TIJMMhZYi3/fPjakpgedY2hoFIemKOUcyfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}