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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a7148983e77300b5df5cf823a3abb428b502f26f22446f44a4a003a3326dfe0b' 
  AND token = '0iGcZS/JWgi7PFVxzVWq6SrMTYs5E8HF2CQ9fonP7EM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}