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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2e08758503ade3c4290265fb15334d495f9410001c5b71753e9a4748e3d9c79a' 
  AND token = 'b1lC1t8+kDrlUVu4t6IMhWlN2t01jOcFD5vXHFN3oWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}