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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd2624ec6f368c7f0879567238d9453af9d56fc1c1228d137bc2b7cee4394f6ad' 
  AND token = 'w357/NnV92aE8/tKhb69jXECUZ3mlrXVWlbWduucvZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}