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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '22ef534b47ddb3be8bb81e6e0406def86e2b027ed6b6cb43776382c056734205' 
  AND token = 'Nrif01dUWrYXbv0whQTc9wZI2/p1VjWh9MW/FTQQeOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}