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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b2bb3668cd05721ef7a7507584352e2697c12c776b819759e5cf7f99afa9b9dc' 
  AND token = 'NE5zYbcUXjPy+BlliMlQ7sDTqSTlIpY4BuWzw+tpva4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}