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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '491ca647c9b5a77987e6894be432471d61852ba214c50333c0a6d5a940576165' 
  AND token = 'GzigMy+5a9SS9B1KxanDQf9mFnG7lrWrMrD9aD/VlXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}