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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f6a170f6d7209103c1e35e24781123935e35f02d6372015ab1355169c72d4a92' 
  AND token = 'JIhOb1mueyRmQxf9Z867JmAXGb3KCOB4UA3Rv7MyOpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}