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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '35ac233308a657f551a41844f04cb8f80cf4d333739d3fa5a48262597d5262b8' 
  AND token = 'aR6o/HukQ+XofjuXAFZUiHfQmmrS4whbkpO1+hlDawk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}